The Short Answer
For general liver support, most people use 250–1,000mg of TUDCA per day, taken with food. Clinical studies have gone higher — up to 1,750mg/day — but those are medical treatment settings, not healthy athletes supporting their liver through hard training. For that goal, the 250–1,000mg range is the commonly referenced sweet spot. FITCNT Liver Support delivers 650mg per daily serving, which sits comfortably inside it.
Here's how to think about the right dose for you.
What the research actually uses
TUDCA has been studied across a surprisingly wide dose range, because the right amount depends entirely on the goal:
- In chronic cholestatic liver disease it's been used at roughly 10–20mg/kg/day (that's ~700–1,600mg for an 80kg adult).
- A metabolic study in obese adults used 1,750mg/day for four weeks.
- Longer clinical trials in other conditions have used 1g twice daily.
The takeaway isn't "take 1,750mg." It's that TUDCA is well-studied and well-tolerated across a broad range — and that therapeutic doses for disease are higher than what a healthy person needs for everyday liver support.
Typical dosing for athletes
If you're training hard, drinking occasionally, or running a demanding supplement routine and you want dedicated liver support:
- 250–500mg/day works as a maintenance dose for general, everyday support.
- 500–1,000mg/day is the range people lean toward during periods of heavier load — high training volume, a surplus, or a supplement cycle.
Start at the lower end, stay consistent, and adjust based on how you respond and any guidance from your healthcare professional.
How and when to take it
- With food. TUDCA is a bile acid, and taking it with a meal fits how your body naturally releases bile.
- With water, ideally a full glass.
- Consistency beats timing. Internal support is a long game — a daily habit matters far more than the exact hour you take it. Splitting a larger dose across two meals is fine if it sits better with you.
Can you take too much?
TUDCA is considered safe and well tolerated in human studies. The side effects reported are generally mild — most commonly loose stools, headache, or mild stomach discomfort, and usually at the higher end of dosing. Starting low and building up is the sensible approach. If you take medication or have a medical condition, talk to your healthcare professional before starting.
How FITCNT doses it
FITCNT Liver Support delivers 650mg of TUDCA per serving, alongside NAC (1,250mg), choline, alpha lipoic acid and zinc — every dose disclosed on the label, no proprietary blends. It's built so a single daily serve covers targeted liver support without you having to stack multiple single-ingredient bottles.
The Bottom Line
For everyday liver support, 250–1,000mg of TUDCA per day with food is the practical range, with 500–1,000mg favoured during heavier training or cycles. Higher doses exist in clinical research but aren't necessary for general support. Buy from a transparent, lab-tested source, check the disclosed dose per serving, and speak with your healthcare professional if you have a condition or take medication.
Want to know how TUDCA stacks up against the other popular option? Read TUDCA vs Milk Thistle: Which Is Better for Liver Support? — and if you're in Australia, Is TUDCA Legal in Australia?
References
- Kars M, et al. "Tauroursodeoxycholic Acid May Improve Liver and Muscle but Not Adipose Tissue Insulin Sensitivity in Obese Men and Women." Diabetes. 2010. PMC
- Hagey LR, et al. "Tauroursodeoxycholic acid." Digestive Diseases and Sciences. 2014. PubMed
- Elia AE, et al. "Tauroursodeoxycholic acid in the treatment of patients with amyotrophic lateral sclerosis." European Journal of Neurology. 2016. PMC
This article is general information only and is not medical advice. Always consult your healthcare professional before starting any supplement. Not suitable for individuals under 18.